Anti-Amyloid beta oligomer-specific monoclonal antibody (OMAB), Biotinylated
SKU: BTL-AGR-A-00942 | Host: Mouse | Brand: Agrisera
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| Cat Number | AS10 932B |
|---|---|
| Category | Primary Antibody |
| Pack Size | 50 µg |
| Description | Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species. |
| Applications | ELISA (ELISA), Immunohistochemistry (IHC) |
| Immunogen | Partly aggregated, recombinant peptide corresponding to the human Abeta (1-40). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V. |
| Clonality | Monoclonal |
| Host | Mouse |
| Form | Lyophilized |
| Molecular Weight | 4.5 kDa |
| Dilution Range | Coating antibody at 2 µg/ml (ELISA), 1 : 500 (IHC) |
| Purity | Affinity purified in PBS pH 7.4. |
| Specie Reactivity | Human Abeta oligomers only |
| Expected Reactivity | Rat |
| Reconstitution | For reconstitution add 100 µl of sterile water |
| Storage | Store lyophilized/reconstituted at 4°C. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |