Anti-ASyO5 | Mouse anti-human alpha-synuclein | oligomer-specific (clone number 2,4)
SKU: BTL-AGR-A-01330 | Host: Mouse | Brand: Agrisera
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| Cat Number | AS13 2718 |
|---|---|
| Category | Secondary Antibody |
| Pack Size | 50 µg |
| Description | Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed. |
| Applications | Dot blot (Dot), ELISA (ELISA), Immunohistochemistry (IHC) |
| Immunogen | Synthetic peptide derived from human alpha-synuclein Gly111-Tyr125 |
| Clonality | Monoclonal |
| Host | Mouse |
| Form | Lyophilized |
| Molecular Weight | 14 kDa |
| Dilution Range | 1-2 µg/ml (Dot), 2-4 µg/ml (ELISA capture), 10 µg/ml (IHC) |
| Purity | Immunogen affinity purified serum in PBS pH 7.4. |
| Specie Reactivity | Human, mouse |
| Reconstitution | For reconstitution add 50 µl of sterile water |
| Storage | For short time storage add sodium azide and store at +4°C. For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |